Company Details
  • Taizhou Volsen Chemical Co., Ltd.

  •  [Zhejiang,China]
  • Business Type:Manufacturer
  • Main Mark: Americas , Asia , East Europe , Europe , North Europe , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:GS, CE, ISO9001, ISO14000
  • Description:Proteasome Inhibitor Ixazomib CAS 1072833-77-2,MLN-2238 MLN2238 CAS 1072833-77-2,HNMR DATE OF Ixazomib 1072833-77-2
Taizhou Volsen Chemical Co., Ltd. Proteasome Inhibitor Ixazomib CAS 1072833-77-2,MLN-2238 MLN2238 CAS 1072833-77-2,HNMR DATE OF Ixazomib 1072833-77-2
Home > Products > Contract Manufacturing > High Purity Ixazomib(MLN-2238; MLN 2238; MLN2238) CAS 1072833-77-2

High Purity Ixazomib(MLN-2238; MLN 2238; MLN2238) CAS 1072833-77-2

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    Unit Price: USD 1 / Kilogram
    Payment Type: T/T
    Incoterm: CIF
    Min. Order: 1 Kilogram
    Delivery Time: 15 Days

Basic Info

Model No.: 1072833-77-2

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

Ixazomib cas number is 1072833-77-2,also named MLN 2238,which is a nitrogen-capped dipeptide leucine boronic acid that inhibits the chymotrypsin (β5) hydrolysis site of the 20S proteasome, with an IC50 of 3.4 nM and a Ki value of 0.93 nM. At higher concentrations, MLN2238 also inhibited the caspase-like hydrolysis (β1) site and the trypsin-like hydrolysis (β2) site of the 20S proteasome with IC50 of 31 nM and 3.5 μM, respectively. MLN2238 Cas 1072833-77-2 is a potent and selective reversible inhibitor of the proteasome, and this reversibility is time dependent. MLN2238 inhibited Calu-6 cells with an IC50 of 9.7 nM. MLN2238 acts on tumor cells and is an effective selective reversible inhibitor of the proteasome. Both MLN2238 and Bortezomib are reversible inhibitors of the proteasome, which are time-dependent, but the separation half-life of MLN2238 on the proteasome is six times faster than that of Bortezomib (18 and 110 minutes, respectively). MLN2238 was isolated from the proteasome faster than Bortezomib and consistent with faster recovery of proteasome activity in the Proteasome-Glo assay. MLN2238 has a higher tumor efficacy than Bortezomib. MLN2238 is a biologically active form of MLN9708.

Thera. Category: Anti-cancer

Cas No.: 1072833-77-2

Synonym:(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid;MLN2238;IxazoMib;B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid;ixazomib(MLN2238);1072833-77-2;B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238);MLN2238(iaxzomib)

MLN-2238 MLN2238 1072833-77-2


Molecular Formula: C14H19BCl2N2O4

Molecular Weight: 361

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request

Usage:

MLN9708 CAS 1201902-80-8 is a selective, potent, and reversible proteasome inhibitor.

1) Ixazomib 1201902-80-8

2) Ixazomib Citrate (MLN9708) CAS 1239908-20-3

3) Ixazomib(MLN-2238; MLN 2238; MLN2238) CAS 1072833-77-2

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Product Categories : Contract Manufacturing

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