Baricitinib Intermediate

MFCD06658411, 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine CAS 84905-80-6

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4-Chloro-5H-pyrrolo[3,2-d]pyrimidine CAS 84905-80-6 is one of the most important intermediate for Baricitinib, which has the molecular formula of C6H4ClN3, formula weight of 153.57 and melting point of 186-188°. Besides to synthesis Baricitinib, 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine CAS NO 84905-80-6 is also widely...

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4-Pyrazoleboronic Acid Pinacol Ester For Baricitinib CAS 269410-08-4

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• Min. Order: 1 Kilogram

Baricitinib intermediate called 4-Pyrazoleboronic acid pinacol ester CAS number is 269410-08-4, his preparation methods are mainly the following two methods. One is use 1-methylpyrazole and isopropanol pinacol boron acid ester as a starting material, reacted with n-butyllithium at -78℃, quenched, washed with water,...

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4-Chloro-7-((2-(Trimethylsilyl)ethoxy)Methyl)-7H-Pyrrolo[2,3-d]pyrimidine CAS 941685-26-3

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• Min. Order: 1 Kilogram

4-Chloro-7-((2-(Trimethylsilyl)ethoxy)Methyl)-7H-Pyrrolo[2,3-d]pyrimidine CAS 941685-26-3 plays an important role in synthesis Baricitinib. Baricitinib, also called LY3009104 and INCB028050, is a potent inhibitor of JAK1 and JAK2. Manufactured 2-[(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)methoxy]ethyl-trimethylsilane...

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High Quality (4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate CAS 1146629-75-5

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(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate CAS 1146629-75-5 is major ingredient for Baricitinib with the molecular formula of C12H14ClN3O2 and formula weight of 267.71146. (4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate CAS NO 1146629-75-5 is widely used to synthesis Baricitinib, a orally...

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Synthesis LY3009104/ INCB028050 Baricitinib Intermediate 1146629-77-7

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[4-(1H-Pyrazol-4-yl)-7H-Pyrrolo[2,3-d]pyrimidin-7-yl]methyl Pivalate is the chemical name of Baricitinib Intermediate CAS 1146629-77-7, which is an important intermediate in our company. The Baricitinib Intermediate 4-(1H-pyrazol-4-yl)-7(2,2-Dimethylpropanoyloxymethyl)-7H-pyrrolo[2,3-d]pyrimidine has the molecular...

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Customization 2-(1-(Ethylsulfonyl)azetidin-3-ylidene)acetonitrile CAS 1187595-85-2

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Baricitinib intermediate called 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile CAS number is 1187595-85-2. There are a lot of literature reports on his synthesis, but there are problems such as high cost and difficult separation. There is a process that is more reliable, the specific process is: In the first...

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Synthesis JAK1 and JAK2 Inhibitor Baricitinib Intermediate CAS 1029716-44-6

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Baritinib intermediate is 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole CAS number 1029716-44-6. There are two main synthetic methods, the first one is use 4-bromo-1-(1-ethoxyethyl)-1H-pyrazole and 2-methoxy-4,4,5,5-four Methyl-1,3,2-dioxaborolan as the starting material, and the target...

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Baricitinib Intermediate 6-Chloro-7-deazapurine CAS 3680-69-1

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Baricitinib Intermediate 4-Chloropyrrolo [2,3-d] pyrimidine, also known as 6-CHLORO-7-DEAZAPURINE, Cas number is 3680-69-1, which is a wide range intermediate of anti-cancer drug, We started production of this product in 2013, it was mainly used for the synthesis of tofacitinib citrate. Our baricitinib intermediate...

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Intermediate of Baricitinib CAS 941685-27-4

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Bariquitinib Intermediate: 4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine Baricitinib advanced intermediates CAS number is 941685-27-4,molecular Formula is C15H21N5OSi , molecular weight is 315.45, it is a white solid, the purity is more than 99 %. Because it is an advanced key...

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Intermediates Baricitinib CAS Number 941685-26-3

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Baricitinib intermediate 5 has the chemical name of 4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE, we generally refer to baricitinib trimethylsilyl, CAS number is 941685-26-3. In the existing process for preparing Baricitinib trimethylsilyl group, 60% sodium hydrogen is used as a base, and...

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Baricitinib Intermediate 8 CAS 1919837-50-5

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• Min. Order: 1 Kilogram

Baricitinib intermediate 8 CAS number is 1919837-50-5 with the chemical name of 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-. In practice, the Baricitinib intermediate 8 often has problems such as difficulty in separation and purification, poor...

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Baricitinib (LY3009104, INCB028050) Intermediates CAS 1153949-11-1

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1-Boc-3-(Cyanomethylene)Azetidine CAS 1153949-11-1, also called Tert-Butyl 3-(Cyanomethylene)azetidine-1-Carboxylate is an useful intermediate for Baricitinib. The purity of 1-Boc-3-(Cyanomethylene)Azetidine CAS NO 1153949-11-1 is more than 98%, and we can offer it by a competitive price....

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