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(Total 12 Products for Potent Atp Competitve Jak Selective Inhibitor 1056634 68 4)
A Potent Inhibitor Indirubin-3'-oxime CAS 160807-49-8
Indirubin-3'-Monoxime CAS 160807-49-8, also called Indirubin-3'-oxime is dark red solid with the purity by HPLC more than 97%. Indirubin-3'-Monoxime CAS NO 160807-49-8 is a potent inhibitor of GSK-3β, Cdk1, and Cdk5, which is soluble in DMSO (>25 mg/ml), 100% ethanol (12 mg/ml), and DMF. Indirubin-3'-Monoxime...
JAK1 and JAK2 Inhibitors Momelotinib(CYT 11387,CYT-387,CYT387)1056634-68-4
Momelotinib CAS 1056634-68-4 is an potent JAK1 and JAK2 Inhibitors acting as an ATP competitive molecule with IC50 values of 11 and 18 nM, respectively. The inhibitor is significantly less active towards other kinases, including JAK3 (IC50 = 0.16 μM). Momelotinib also named as CYT 11387,CYT-387,CYT387, CYT-387 has the...
Potent LpxC Inhibitor CHIR-090 CAS 728865-23-4
CHIR-090 CAS 728865-23-4 also called CHIR090 and CHIR 090 is a greatly potent, tight-binding inhibitor of LpxC., which has antimicrobial property. CHIR-090 CAS NO 728865-23-4 has the molecular formula of C24H27N3O5, formula weight of 437.48828 and the purity of it is more than 99%. The CHIR-090 CAS 728865-23-4 has...
Potent VEGFR2 Inhibitor of Vandetanib CAS 443913-73-3
Vandetanib CAS NUMBER is 443913-73-3 is a multi-target tyrosine kinase inhibitor, belongs to aniline quinazoline compounds, as known as "second generation IRESSA". It is the first approved mediastinal thyroid cancer treatment drug that is suitable for the treatment of unresectable, locally advanced or metastatic...
Rucaparib (AG-014699/ PF-01367338), A Potent PARP1 Inhibitor CAS 459868-92-9
PF-01367338 CAS No. 459868-92-9, also known as AG-14699 and Rucaparib, is a potent PARP1 inhibitor with anti-cancer property. Addition to this, Rucaparib 459868-92-9 may also enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. The AG-14699 CAS...
4-Chloro-7-((2-(Trimethylsilyl)ethoxy)Methyl)-7H-Pyrrolo[2,3-d]pyrimidine CAS 941685-26-3
4-Chloro-7-((2-(Trimethylsilyl)ethoxy)Methyl)-7H-Pyrrolo[2,3-d]pyrimidine CAS 941685-26-3 plays an important role in synthesis Baricitinib. Baricitinib, also called LY3009104 and INCB028050, is a potent inhibitor of JAK1 and JAK2. Manufactured 2-[(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)methoxy]ethyl-trimethylsilane...
A Potent JAK1 and JAK2 Inhibitor Baricitinib CAS 1187594-09-7
Baricitinib (olumiant) has the cas number of 1187594-09-7 is a selective JAK2 and JAK1 inhibitor that targets multiple active rheumatoid arthritis-associated cytokine pathways, thereby reducing the activation and proliferation of key immune cells in inflammatory cells. It is mainly used to treat moderate to severe...
MFCD09032505, Potent Intermediate of Laquinimod CAS 637027-41-9
Methyl 5-Chloro-4-Hydroxy-1-Methyl-2-Oxo-Quinoline-3-Carboxylate CAS 637027-41-9 plays an important role in synthesis Laquinimod. Laquinimod is a potent and orally-available immunomodulator widely used to treatment of multiple sclerosis (MS). Laquinimod Intermediate CAS NO 637027-41-9 has the molecular formula of...
Antifungal Potent Echinocandin B CAS 54651-05-7
Echinocandin B CAS number is 54651-05-7,Molecular formula of C53H83N7O16,Molecular weight of 1074.27 which is a naturally occurring cyclic hexapeptide with an acyl side chain. It belongs to a class of antifungal drugs called echinodermycin, which is a major component of non-competitive inhibition of a key enzyme beta...
Potent FP Receptor Bimatoprost (AGN 192024) Cas Number 155206-00-1
Bimatoprost cas number 155206-00-1 is a second-generation pro- glaucoma-resistant glaucoma drug that has become a first-line anti-glaucoma preparation in most parts of the world. Unlike latanoprost and travoprost, it is a synthetic prostaglandin that selectively mimics the action of naturally occurring prostaglandins...
Synthesis JAK1 and JAK2 Inhibitor Baricitinib Intermediate CAS 1029716-44-6
Baritinib intermediate is 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole CAS number 1029716-44-6. There are two main synthetic methods, the first one is use 4-bromo-1-(1-ethoxyethyl)-1H-pyrazole and 2-methoxy-4,4,5,5-four Methyl-1,3,2-dioxaborolan as the starting material, and the target...
JAK Pathway Inhibitor Tofacitinib Citrate CAS Number 540737-29-9
Tofacitinib citrate CAS Number is 540737-29-9, which is a novel oral JAK pathway inhibitor developed by Pfizer. Unlike most other current rheumatoid arthritis treatments that act primarily on extracellular targets, tofacitinib citrate targets the intracellular signal transduction pathway and acts on the core of the...
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Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.