Taizhou Volsen Chemical Co., Ltd.
HomeProductsPharmaceutical IntermediatesAnti-Tumor/CancerAfatinib N-2, CAS Number 314771-76-1

Afatinib N-2, CAS Number 314771-76-1

  • $2000
    ≥1
    Kilogram
Payment Type:
T/T
Incoterm:
CIF
Min. Order:
1 Kilogram
Transportation:
Air,DHL
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  • Product Description
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Product Attributes

Model No. 314771-76-1

BrandVOLSENCHEM

Supply Ability & Additional Information

PackagingAS REQUIRED

ProductivityKGS

TransportationAir,DHL

Place of OriginCHINA

Supply AbilityTRUE MANUFACTURER

CertificateISO

Payment TypeT/T

IncotermCIF

Packaging & Delivery
Selling Units:
Kilogram
Package Type:
AS REQUIRED
Afatinib minus two intermediate, we referred it as afatinib N-2, CAS number is 314771-76-1, which is a high-level intermediate of afatinib, later only through two steps reaction to get afatinib. There are two main synthesis ideas in the literature, the first, put the bromo crotonic acid and oxalyl chloride take reaction to get the acid chloride and then process acylation with afatinib N-2, followed by adding dimethylamine to obtain afatinib. This method yield up to only 50%, in addition need...

Product Categories : Pharmaceutical Intermediates > Anti-Tumor/Cancer

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