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(Total 12 Products for Nintedanib Intermediate 676326 36 6)
Nintedanib OR BIBF 1120 CAS number 656247-17-5
Nintedanib is referred to as BIBF 1120 CAS number is 656247-17-5, molecular weight is C31H33N5O4 molecular formula is 539.62482. Nintedanib is an oral administration of triple tyrosine kinase inhibitors, targets include platelet-derived growth factor (PDGF), vascular endothelium Growth factor (VEGF) and basic...
CAS 928326-83-4,Vargatef Base or BIBF-1120,BIBF 1120,BIBF1120
Nintedanib referred to as Vargatef Base or BIBF-1120,BIBF 1120,BIBF1120, CAS number is 928326-83-4. It is an anti-tumor drug. In the treatment of idiopathic pulmonary fibrosis (IPF) worthy of our expectations. IPF is a fatal lung disease that is severely endangered by humans, with a median survival after diagnosis of...
CAS 676326-36-6,Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Intermediate of Nintedanib called Methyl 1-acetyl-2-oxoindoline-6-carboxylate CAS number is 676326-36-6, Molecular formula of C12H11NO4, Molecular weight of 233. Nintedanib and its intermediates are relatively new compounds, but it is a mature products in our company. Our Nintedanib intermediate CAS 676326-36-6 has...
Methyl 2-oxoindole-6-carboxylate Used for Nintedanib CAS 14192-26-8
Methyl 2-oxoindole-6-carboxylate CAS 14192-26-8,His synthesis is mainly divided into two steps, the specific operation process is as follows: The first step: 200g (1mol) 4-chloro-3-nitrobenzoic acid suspended in methanol, added 59g (490mmol) Thionyl Chloride within 15min, heated under reflux and reacted for 3 hours at...
Nintedanib Ethanesulfonate Salt CAS number is 656247-18-6 is an oral triple-acting vascular kinase inhibitor developed by Boehringer Ingelheim and was approved by the FDA in October 2014 for the treatment of idiopathic pulmonary fibrosis (IPF), becoming the first tyrosine kinase inhibitor (TKI) approved for the...
2-Oxindole-6-carboxylic Acid Methyl Ester Used for Making Nintedanib 14192-26-8
Nintedanib intermediate,full chemical name is 2-Oxindole-6-carboxylic acid methyl ester CAS number 14192-26-8, in numerous patent reports,it is the starting material for the synthesis of nintedanib, the general process of synthesis of nintedanib As follows: Nintedanib was obtained by the steps of replacing,...
Nintedanib Intermediate 3 CAS Number 1160293-25-3
Nintedanib intermediate 3 CAS number is 1160293-25-3, with chemical name of 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester, his synthetic route is as follows: 1. 4-chloro-3-nitrobenzoic acid was suspended in methanol, after adding thionyl chloride ,take heating and refluxing reaction,...
The Nintedanib intermediate 5,CAS 1168150-46-6
The Nintedanib intermediate 5 as known as BIBF1120 CAS number is 1168150-46-6, which can obtain by simply deprotecting our already existing Nintedanib intermediate 4, The process is as follows: In a 500ml three-necked flask was added 84g Nintedanib intermediate 5 CAS number 1168150-46-6, 225ml of methanol, heated to...
Nintedanib Intermediate 6 CAS Number 656247-17-5
Nintedanib intermediate 6 CAS number is 656247-17-5, which can obtain by simply condensing with the relevant product on the basis of nintedanib intermediate 5. The specific experimental procedure is as follows: In a 100 ml three-necked reaction flask, added 5.0 g of nintedanib intermediate 5, 8.9 g of N-...
Nintedanib Side Chain CAS Number 262368-30-9
Nintedanib side chain CAS number is 262368-30-9, it has been reported in the literature to use N-methyl-4-amino-nitrobenzene as raw material, with chloroacetyl chloride reaction to form amide, the treated amide and N-methyl piperazine Oxazine take reaction, after the reaction was completed and then hydrogenated to...
We,China BP-984 135261-74-4 Suppliers and China BP-984 135261-74-4 Manufacturers, provide BP-984 135261-74-4 product. Backed by rich industry experience, we are engaged in offering an excellent range of Drugs Intermediates & Pharmaceuticals. These drugs intermediates & pharmaceuticals are extensively used in...
We are professional 2-Methoxy-4-Amino-5-Ethylsulfonylbenzoic Acid CAS. No.71675-87-1 manufacturers and suppliers in China. which is an intermediate of Amisulpride.These high quality products are formulated by adopting quality methods and using well-tested ingredients that are procured from the certified vendors of the...
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Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.