Sitafloxacin Intermediate 127199 00 2

Fluoroquinolone Antibiotic Sitafloxacin Intermediate CAS 127199-45-5

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SITAFLOXACIN intermediate (S)-7-tert-Butoxycarbonylamino-5-azaspiro[2.4]heptane CAS number 127199-45-5, its synthesis ideas are the following: Firstly, synthesis of racemate of (S)-7-tert-Butoxycarbonylamino-5-azaspiro[2.4]heptane, and then split to get a single configuration of compounds, This method creates another...

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Sitafloxacin Hydrate Treatment for Infectious Diseases Cas Number 163253-35-8

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Sitafloxacin hydrate cas number 163253-35-8, is a quinolone broad-spectrum antimicrobial, it is used for the treatment of severe refractory infectious diseases, sitafloxacin cas 163253-35-8 can be developed into oral administration or injected. Due to the molecular structure contains a cisfluorocarbamidine group, and...

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SITAFLOXACIN Intermediate 7 CAS 144282-37-1

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SITAFLOXACIN intermediate 7 has the chemical name of Carbamic acid, [(7S)-5-(phenylmethyl)-5-azaspiro[2.4]hept-7-yl]-, 1,1-dimethylethyl ester CAS number 144282-37-1, Synthetic method is as follows: First, ethyl acetoacetate is added to the kettle and then add DMF, 1,2-dibromoethane, potassium carbonate by turn, After...

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(1R,2S)-FLUOROCYCLOPROPYLAMINE TOSYLATE For SITAFLOXACIN CAS Number 143062-84-4

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SITAFLOXACIN intermediate also known (1R,2S)-FLUOROCYCLOPROPYLAMINE TOSYLATE CAS number 143062-84-4, in the "China Pharmaceutical Industry magazine" published in 2006 on the 36th page recorded the "sitafloxacin synthesis route diagram" and described a series of synthetic methods of sitafloxacin, which lists a variety...

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Broad Antibacterial Spectrum Drus Sitafloxacin CAS 127254-10-8

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Sitafloxacin CAS number is 127254-10-8, It is a fourth-generation fluoroquinolones,it first marketed in Japan in 2008 for the treatment of severe refractory infectious diseases, there are two dosage forms in 50mg tablets and 10% fine-particle. It can inhibit the bacterial DNA gyrase and topoisomerase IV, and the...

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(1R, 2S)-fluorocyclopropylamine hydrochloride Used For Sitafloxacin CAS 141042-21-9

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Sitafloxacin side chain intermediate (1R, 2S)-fluorocyclopropylamine hydrochloride CAS number is 141042-21-9, his synthesis process is as below: 1. Synthesis of a three-membered ring. 1 kg of methyl 4-chloroacetoacetate was dissolved in 6 L of acetonitrile, and 38 g of valine and 1.25 kg of 1,2-dibromoethane were...

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3-Chloro-2,4,5-Trifluorobenzoic Acid For Sitafloxacin CAS Number 101513-77-3

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3-Chloro-2,4,5-trifluorobenzoic acid CAS number is 101513-77-3, which is a key intermediate for the synthesis of new fluoroquinolones such as Sitafloxacin. 3-Chloro-2,4,5-trifluorobenzoic acid, as an important synthetic intermediate for new antibacterial drugs, has broad market development prospects. His synthesis...

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ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE Used For Sitafloxacin CAS 101987-86-4

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Sitafloxacin intermediate ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE CAS number is 101987-86-4, his synthetic process is as follows: 1.500ml four-necked flask was added 21g of 3-chloro-2,4,5-trifluorobenzoic acid, 210ml of dichloromethane and 1ml of DMF, stirred until dissolved, cooled to 0-10 ° C, and...

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6,7-Difluoro-1-((1R,2S)-2-Fluorocyclopropyl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid 127199-00-2

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Sitafloxacin intermediate cis-(+)-6,7-Difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid CAS number is 127199-00-2, his synthesis process is as follows: 1. Dissolve 84 g of 2,4,5-trifluoro-3-chlorobenzoic acid in 252 mL of DMF, add 55.8 g of oxalyl chloride, and react at 35 ° C for 2 h. The...

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8-chloro-6,7-difluoro-1-((1R,2S)-2-Fluorocyclopropyl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid 127199-27-3

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Sitafloxacin intermediate 8-chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS number is 127199-27-3, his manufacturing process is as follows: 1. Under the protection of nitrogen, 20.9 g of ethyl 2,4,5-trifluorobenzoyl acetate, 1.5 g of cuprous iodide, 2.9 g of...

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(1R,2R)-2-Fluorocyclopropanecarboxylic Acid For Sitafloxacin CAS 127199-13-7

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(1R,2R)-2-fluorocyclopropanecarboxylic acid is an intermediates of Sitafloxacin CAS number 127199-13-7. A simple and efficient method for preparing (1R, 2R) -2-fluorocyclopropanecarboxylic acid is as follows: The racemic 2-fluorocyclopropanecarboxylic acid was resolved by using (-)-strychnine,(...

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(1R,2S)-2-Fluorocyclopropanecarboxylic Acid For Sitafloxacin CAS 167073-08-7

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Sitafloxacin intermediate has chemical name of (1R,2S)-2-fluorocyclopropanecarboxylic acid CAS 167073-08-7,Molecular formula is C4H5FO2,molecular weight is104.0797. Thera. Category: Anti-infection Cas No.: 167073-08-7 Synonym:

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