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HomeProductsOther ChemicalsMethyl 2-oxoindole-6-carboxylate Used for Nintedanib CAS 14192-26-8

Methyl 2-oxoindole-6-carboxylate Used for Nintedanib CAS 14192-26-8

Payment Type:
L/C,T/T
Incoterm:
FOB,CIF,CPT
Min. Order:
1 Kilogram
Transportation:
Ocean,Air
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Product Attributes

Model No.14192-26-8

BrandVOLSENCHEM

Supply Ability & Additional Information

PackagingAS REQUIRED

ProductivityKGS

TransportationOcean,Air

Place of OriginCHINA

Supply AbilityTRUE MANUFACTURER

Payment TypeL/C,T/T

IncotermFOB,CIF,CPT

Packaging & Delivery
Selling Units:
Kilogram
Package Type:
AS REQUIRED
Methyl 2-oxoindole-6-carboxylate CAS 14192-26-8,His synthesis is mainly divided into two steps, the specific operation process is as follows: The first step: 200g (1mol) 4-chloro-3-nitrobenzoic acid suspended in methanol, added 59g (490mmol) Thionyl Chloride within 15min, heated under reflux and reacted for 3 hours at 70℃ and then cooled to 5℃. The product was isolated by centrifugation and dried at 45℃ to give 189.2 g of a solid as a first step, 4-chloro-3-nitrobenzoate ester. Second...

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