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HomeProductsOther ChemicalsAcetylcholine Muscarinic Receptors Scopolamine Hydrobromide CAS 114-49-8
Acetylcholine Muscarinic Receptors Scopolamine Hydrobromide CAS 114-49-8
  • Acetylcholine Muscarinic Receptors Scopolamine Hydrobromide CAS 114-49-8

Acetylcholine Muscarinic Receptors Scopolamine Hydrobromide CAS 114-49-8

Basic Info

Model No.: 114-49-8

Product Description

Scopolamine hydrobromide CAS number 114-49-8, the appearance of colorless transparent crystal or white crystalline powder, he is a strong peripheral anticholinergic agent, blocking M choline receptor. His peripheral effect is stronger than atropine and maintains a short period of time. It can inhibit glandular secretion, relieve capillary spasm, improve microcirculation, dilate bronchial tubes, relieve smooth muscle spasm, and have sedative, hypnotic and excitatory effects on the cerebral cortex. Clinically used for pre-anesthesia administration, tremor palsy, motion sickness, manic psychosis, gastrointestinal biliary and renal smooth muscle spasm, excessive gastric acid secretion, septic shock and organophosphorus pesticide poisoning.
Scopolamine hydrobromide CAS number 114-49-8 can prevent halo and antiemetic by reducing the stress of the labyrinth receptor and inhibiting the conduction of the vestibular cerebellar pathway, and is clinically used as a prevention and treatment of motion sickness. The scopolamine hydrobromide preparations mainly include oral, tablet, and nasal sprays. Oral or tablet administration has the effects of slow onset of pharmacodynamics, loss of efficacy due to vomiting during oral administration, high cost of use, and inconvenience in carrying and use. Later, people began to study a new type of anti-motion drug for nasal administration with scopolamine hydrobromide as the main component. The use of nasal administration can avoid the first-pass effect of the liver, rapid absorption and high bioavailability. For example, Nastech's scopolamine hydrobromide nasal spray can prevent and treat motion sickness. In a phase III clinical study, the incidence of motion sickness after short-term voyages was significantly less than that of placebo. The duration of action can last from 6 to 8 hours.

Thera. Category: Muscarinic Antagonist

Cas No.: 114-49-8

Synonym:Hyoscine hydrobromide; Scopine tropate;Atroscine Hydrobromide


Molecular Formula:C17H22BrNO4

Molecular Weight:384.26

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request

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Product Categories : Other Chemicals

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