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Preparing Method of Avanafil Intermediate 3 CAS 330785-81-4

$1

≥1
Kilogram

Payment Type:

T/T

Incoterm:

CIF

Min. Order:

1 Kilogram

Transportation:

Air

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Product Description

Product Attributes
Supply Ability & Additional Information
Packaging & Delivery

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Overview

Product Attributes

Model No.: 330785-81-4

Brand: VOLSENCHEM

Function: Nervous System Drugs

Supply Ability & Additional Information

Packaging: AS REQUIRED

Productivity: KGS

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Payment Type: T/T

Incoterm: CIF

Packaging & Delivery

Selling Units:: Kilogram

Package Type:: AS REQUIRED

Avanafil intermediate 3 CAS number is 330785-81-4, which is a key intermediate for Avanafil. His traditional preparation method is using ethyl 4-hydroxy-2-methylthio-5-pyrimidinecarboxylate as a raw material, and then chlorination to form ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate. Further, an amino group substitution reaction with (3-chloro-4-methoxy)benzylamine gives the product Avanafil intermediate 3. The chlorination reaction in this method is the key part of the whole preparation...

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