Company Details
  • Taizhou Volsen Chemical Co., Ltd.

  •  [Zhejiang,China]
  • Business Type:Manufacturer
  • Main Mark: Americas , Asia , East Europe , Europe , North Europe , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:GS, CE, ISO9001, ISO14000
  • Description:Intraocular Pressure Intermediates of Brinzolamide 154127-42-1,High Purity Brinzolamide Intermediate CAS 154127-42-1,154127-42-1
Taizhou Volsen Chemical Co., Ltd. Intraocular Pressure Intermediates of Brinzolamide 154127-42-1,High Purity Brinzolamide Intermediate CAS 154127-42-1,154127-42-1
Home > Products > Contract Manufacturing > (4S)-1,1-Dioxide-3,4-Dihydro-4-Hydroxy-2-(Brinzolamide Intermediate) CAS 154127-42-1

(4S)-1,1-Dioxide-3,4-Dihydro-4-Hydroxy-2-(Brinzolamide Intermediate) CAS 154127-42-1

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    Unit Price: USD 1 / Kilogram
    Incoterm: CIF
    Min. Order: 1 Kilogram
    Delivery Time: 15 Days

Basic Info

Model No.: 154127-42-1

Additional Info

Packaging: As required

Productivity: 10KG/M


Transportation: Air

Place of Origin: CHINA

Certificate: Technical Support

Product Description

Brinzolamide dioxide is a high-level intermediate of Brinzolamide. Its reaction step is long and at least through five steps to get it. There is one feasibility method, with 3-Acetyl-2,5-dichlorothiophene as raw materials, adding sulfite to get the form of sodium sulfite compounds, and then react with 3-methoxy amino propane to get p-aminobenzenesulfonamide compound, then put the compound react with ethylene glycol to get the corresponding compound and then reacting with the organometallic compound, followed by treatment with sulfuric acid followed by treatment with hydroxylamine-O-sulfonic acid to give a sulfadiazine-containing compound and carrying out the oxidative compound Acetyl group, followed by reaction with pyridinium bromide to give an intermediate containing CH2Br. Under basic conditions, the compound containing CH2Br is reacted with the chiral reducing agent (+) - di-3-pinylchloroborane to get the target Compounds.

(4S)-1,1-Dioxide-3,4-Dihydro-4-Hydroxy-2- CAS 154127-42-1 is an important product in our company and it is also a vital intermediate for Brinzolamide. Brinzolamide Intermediate CAS NO 154127-42-1 is white powder which purity is more than 98% with the boiling point of 612.4℃, molecular formula of C10H16N2O6S3 and formula weight of 356.44. As we all known, Brinzolamide, as a carbonic anhydrase inhibitor, is widely used to treatment of open-angle glaucoma or ocular hypertension. We can offer the Brinzolamide with a competitive price.

Thera. Category:Anti- hypertension.

Cas No.:154127-42-1

Synonyms: (4S)-1,1-dioxide-3,4-dihydro-4-hydroxy-2-;(4S)-1,1-dioxide-3,4-dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide;(S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; (S)-2-(3-Methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-4-ol-6-sulfonaMide-1,1- dioxide

NW: 356.44

M.W.: C10H16N2O6S3


Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: Intermediate of Brinzolamide

Looking for ideal Intraocular Pressure Intermediates of Brinzolamide 154127-42-1 Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the High Purity Brinzolamide Intermediate CAS 154127-42-1 are quality guaranteed. We are China Origin Factory of 154127-42-1. If you have any question, please feel free to contact us.

Product Categories : Contract Manufacturing

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