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(Total 12 Products for Nintedanib Vegfr Pdgfr Fgfr Inhibitor Cas928326 83 4)
Nintedanib OR BIBF 1120 CAS number 656247-17-5
Nintedanib is referred to as BIBF 1120 CAS number is 656247-17-5, molecular weight is C31H33N5O4 molecular formula is 539.62482. Nintedanib is an oral administration of triple tyrosine kinase inhibitors, targets include platelet-derived growth factor (PDGF), vascular endothelium Growth factor (VEGF) and basic...
CAS 928326-83-4,Vargatef Base or BIBF-1120,BIBF 1120,BIBF1120
Nintedanib referred to as Vargatef Base or BIBF-1120,BIBF 1120,BIBF1120, CAS number is 928326-83-4. It is an anti-tumor drug. In the treatment of idiopathic pulmonary fibrosis (IPF) worthy of our expectations. IPF is a fatal lung disease that is severely endangered by humans, with a median survival after diagnosis of...
Methyl 2-oxoindole-6-carboxylate Used for Nintedanib CAS 14192-26-8
Methyl 2-oxoindole-6-carboxylate CAS 14192-26-8,His synthesis is mainly divided into two steps, the specific operation process is as follows: The first step: 200g (1mol) 4-chloro-3-nitrobenzoic acid suspended in methanol, added 59g (490mmol) Thionyl Chloride within 15min, heated under reflux and reacted for 3 hours at...
Nintedanib Ethanesulfonate Salt CAS number is 656247-18-6 is an oral triple-acting vascular kinase inhibitor developed by Boehringer Ingelheim and was approved by the FDA in October 2014 for the treatment of idiopathic pulmonary fibrosis (IPF), becoming the first tyrosine kinase inhibitor (TKI) approved for the...
2-Oxindole-6-carboxylic Acid Methyl Ester Used for Making Nintedanib 14192-26-8
Nintedanib intermediate,full chemical name is 2-Oxindole-6-carboxylic acid methyl ester CAS number 14192-26-8, in numerous patent reports,it is the starting material for the synthesis of nintedanib, the general process of synthesis of nintedanib As follows: Nintedanib was obtained by the steps of replacing,...
Nintedanib Intermediate 4,Cas 1174335-83-1
Nintedanib intermediate 4 CAS number is 1174335-83-1, the general operation is taking reaction of 2-Oxindole-6-carboxylic acid methyl ester and acid chlorination reagent chloroacetic anhydride to get chloride compound, then the compound and the original three Methyl ester to take condensation to obtain the target...
The Nintedanib intermediate 5,CAS 1168150-46-6
The Nintedanib intermediate 5 as known as BIBF1120 CAS number is 1168150-46-6, which can obtain by simply deprotecting our already existing Nintedanib intermediate 4, The process is as follows: In a 500ml three-necked flask was added 84g Nintedanib intermediate 5 CAS number 1168150-46-6, 225ml of methanol, heated to...
Nintedanib Intermediate 6 CAS Number 656247-17-5
Nintedanib intermediate 6 CAS number is 656247-17-5, which can obtain by simply condensing with the relevant product on the basis of nintedanib intermediate 5. The specific experimental procedure is as follows: In a 100 ml three-necked reaction flask, added 5.0 g of nintedanib intermediate 5, 8.9 g of N-...
Potent VEGFR2 Inhibitor of Vandetanib CAS 443913-73-3
Vandetanib CAS NUMBER is 443913-73-3 is a multi-target tyrosine kinase inhibitor, belongs to aniline quinazoline compounds, as known as "second generation IRESSA". It is the first approved mediastinal thyroid cancer treatment drug that is suitable for the treatment of unresectable, locally advanced or metastatic...
VEGFR Inhibitor Tivozanib(AV-951,KRN951) CAS 475108-18-0
Tivozanib(AV-951) cas number 475108-18-0 is an anti-tumor targeted therapy, a multi-target anti-angiogenesis inhibitor,as anti-cancer new drug, mainly used for the treatment of renal cancer, showing good curative effect in the first-line treatment of advanced renal cell carcinoma. The main target is vascular...
Ataluren CAS 775304-57-9 is an important product in our company, formerly known as PTC124. We offer superior quality Ataluren, which occupy the main position in treatment of Duchenne muscular dystrophy and potentially other genetic disorders. Ataluren CAS NO 775304-57-9, supplied by us, is repeated test by our experts...
254964-60-8,Tasquinimod(ABR 215050)
We are offering in wide range of Pharmaceutical 254964-60-8,Tasquinimod. These high quality products are formulated by adopting quality methods and using well-tested ingredients that are procured from the certified vendors of the market. We offer these products in proper packaging of diverse quantity to meet assorted...
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