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Taizhou Volsen Chemical Co., Ltd.
HomeProductsPharmaceutical IntermediatesAnti-Diabetes2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole For Omarigliptin 1280210-80-1
2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole For  Omarigliptin 1280210-80-1
  • 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole For  Omarigliptin 1280210-80-1

2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole For Omarigliptin 1280210-80-1

    Unit Price: USD 1 / Kilogram
    Payment Type: T/T
    Incoterm: CIF
    Min. Order: 1 Kilogram
    Delivery Time: 15 Days

Basic Info

Model No.: 1280210-80-1

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

Omarigliptin (MK-3102) intermediate has the chemical name of 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole, CAS number is 1280210-80-1, molecular formula: C12H15N3O5S2, molecular weight: 345.39, his synthesis process is adding 3.3Kg benzenesulfonic acid to 14 L of ethyl acetate to dissolve, and circulate the frozen brine to 5 to 15℃; 2.85 Kg of 2-(methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3 , 4-C]pyrazole besylate was added to 14 L of ethyl acetate to dissolve, and added to the solution of benzenesulfonic acid and ethyl acetate at 5 to 15 ℃, stirred for 30 minutes, and then dehydrated to 25 ± 5℃ After stirring at for 16 hours, the solid was obtained by centrifugation. The solid was added to 17 L of ethyl acetate and stirred for 1.5 hours. After centrifugation, the solid was washed with 4 L of ethyl acetate. The wet product was dried at -0.08 MPa to -0.1 MPa, and vacuum dried at 40 ℃ for 8 hours. The yellow solid compound was 3.16 Kg. This pale yellow solid compound was the Omarigliptin (MK-3102) intermediate 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole CAS 1280210-80-1.

Thera. Category:Anti Diabetes

Cas No.: 1280210-80-1

Synonym: 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole;2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole benzenesulfonate;MK-3102 interMediate;2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-5-iuM benzenesulfonate;2,4,5,6-Tetrahydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazole benzenesulfonate;Omarigliptin inter. OG-2;MK-3102 intermediate3;2-Methanesulfonyl-2,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazole Benzenesulfonic acid salt

Molecular Formula:C12H15N3O5S2

1280210-80-1

Molecular Weight:345.39

Assay: ≥98.%

Appearance: White Crystalline solid

Storage: normal

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Related Intermediate:

1)N-[(2R,3S)-2-(2,5-difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]-CarbaMic acid 1,1-diMethylethyl ester 951127-25-6

2)2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole, CAS 1280210-80-1,

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Product Categories : Pharmaceutical Intermediates > Anti-Diabetes

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